Research Activities
Last Updated:
18/03/2022 - 15:33
- Purification, biochemical and immunological characterization of microsomal drug metabolizing enzyme systems (NADPH dependent cytochrome P-450 reductase; cytochrome P-450 isozymes; Flavin monooxygenases, and conjugation enzymes (glutathione-S-transferases; N-acetyl transferases)
- Purification and characterization of lung microsomal cytochrome b5 and NADH cytochrome b5 reductase and their interaction with drug metabolizing enzymes.
- Identification and characterization of stress proteins (heat, cold, metal and salt) in different crop plants; genetic manipulation of crop plants.
- Application of new technologies on destruction of food microorganisms; identification of food microorganisms, hazard analysis.
- Control of malo-lactic fermentation.
- Polymorphism of drug metabolism in human (glutathione-S-transferases; N-acetyl transferases, P-450, FMO)
- Structure function studies on flavin containing monooxygenases.
- Cytochrome P-450 dependent drug metabolism in diabetic animals.
- Genotoxicity and DNA interactions of metals, free radicals and newly synthesized anticancer agents.
- Enzyme kinetics; kinetic studies on regulatory enzymes.
- Biochemical characterization of signal transduction pathways in plants.
- Enzyme technology; large scale production, purification and characterization of industrially important enzymes.
- Protein conformation and stability; protein modification; metal and ligand binding; circular dichroism and fluorescence techniques.
- Design and synthesis of artificial enzymes and fluorescent chemosensors.
- Molecular marker isolation (such as AFLP) for mapping and genotyping of crop plants.
- Analysis of anti-sense reagents.
- Effects of vitamin E on erythrocyte membrane structure and stability.
- Studying the molecular basis of individual variation in working and reference memory in different rat strains
- Studies on the role of some pharmacological agents as a therapeutic tool in memory deficits in young and old animals.
- Monitoring microbial catabolic enzymes to degrade pollutants
- Bioremediation of xenobiotics
- Food biochemistry, antioxidants, food polymers